For artists and designers using Flickr to document and share their work, this development means that their non-photographic images are now second-class citizens. If Flickr goes any further in censoring non-photographic images, it would make Flickr unattractive for sharing anything beyond holiday snaps. I honestly don't understand what they are hoping to gain by this strategy, as non-photographic images don't present any problems unless there is a copyright violation. Nor do I understand why screenshots or CGI images would be unsuitable for a public audience.
Now, being "reviewed as safe" sounds like good a good thing, so I thought I'd go one step further and mark all my non-photographic images as such. Flickr calls this "moderating your photostream". One of the side effects seems to be that all my non-photographic images are no longer available in public searches. You can observe it by searching for the title "Randbox". It won't show any results, meaning that my RandBox images are now NIPSA'ed. They can still be found via my photostream, but not through searching. Any non-photo images that were in Flickr's Explore are no longer there.