shankargallery (shankargallery) wrote,

Prions of fungi

Prions of fungi

Posted by ajcann on August 17th, 2007

Prion protein
  • [URE3] is a prion of the nitrogen catabolism regulator Ure2p

  • [PSI+] is a prion of the translation-termination factor Sup35p, which has a parallel beta-sheet structure.

  • [PIN+] is a prion of Rnq1p (function unknown)

  • [Het-s] is a prion of the heterokaryon incompatibility protein HETs; this prion of apparently benefits its host (Podospora anserina), whereas the [URE3] and [PSI+] prions of Saccharomyces cerevisiae are detrimental.

  • [β] is a prion of vacuolar protease B

  • [C] is a prion of a mitogen-activated protein kinase kinase kinase
  • There are six known prions of fungi, including four self-propagating amyloids and two enzymes that are necessary to activate their inactive precursors:


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